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Masters Thesis

An investigation of lipoic acid and it's [its] derivative as potential ligands for PPARs

This study sought to determine the effects of a-Lipoic Acid (LA) and the prodrug, LA-ester (LA-E1) on a variety of PPAR mediated events including PPAR activity, adipogenesis, gene expression and cellular proliferation. The study also looks at the ability of LA-E1 to improve PPAR activity or efficacy (maximal activation) and modulate the expression of PPAR-regulated target genes.
Date
  • 2006-09-01
Resource Type
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Degree Level
  • Masters
Degree Name
  • M.S.
Degree Program
  • Biological Sciences
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